Makeeva V F, Komolova G S, Egorov I A, Isabaeva V A
Kosm Biol Aviakosm Med. 1978 May-Jun;12(3):56-60.
Adaptation to altitude hypoxia exerts a positive effect on the cell density of lymph organs of gamma-irradiated animals. It also reduces radiation degradation of DNA, its availability to DNase in the nuclear chromatin and disorders in the activity of DNA polymerases. The role of inhibition of radiation-induced degradation of chromatin DNA in the protective effect of altitude adaptation on the cell density of lymph organs is discussed.
适应高原低氧对γ射线照射动物淋巴器官的细胞密度具有积极影响。它还能减少DNA的辐射降解、核染色质中DNA对脱氧核糖核酸酶的可及性以及DNA聚合酶活性的紊乱。本文讨论了抑制染色质DNA的辐射诱导降解在高原适应对淋巴器官细胞密度的保护作用中的作用。
