Henderson Cassandra E, Hana Romany Gawargious, Woroch Roman, Reilly Kevin D
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Montefiore North Division Medical Center, Albert Einstein College of Medicine, Bronx, New York 10466, USA.
J Reprod Med. 2010 Jul-Aug;55(7-8):362-4.
Short interpregnancy interval and uterine instrumentation are risk factors for uterine rupture in subsequent pregnancies. Misoprostol as a uterotonic agent is an additive risk factor for rupture of a scarred uterus.
Misoprostol induction for a term stillbirth was complicated by uterine rupture. Risk factors for this uterine rupture might have included interpregnancy intervals of < 7 months, prior uterine instrumentation, and misoprostol as a uterotonic agent.
Caution and a high index of suspicion are warranted when using misoprostol as a uterotonic agent after a short interpregnancy interval.
妊娠间隔短和子宫手术操作是后续妊娠子宫破裂的危险因素。米索前列醇作为宫缩剂是瘢痕子宫破裂的一个附加危险因素。
米索前列醇引产足月死产并发子宫破裂。此次子宫破裂的危险因素可能包括妊娠间隔小于7个月、既往子宫手术操作以及使用米索前列醇作为宫缩剂。
妊娠间隔短后使用米索前列醇作为宫缩剂时,应谨慎并保持高度怀疑。