Kurban Mazen, Abbas Ossama, Ghosn Samer, Kibbi Abdul-Ghani
Dermatology Department, American University of Beirut Medical Center, Beirut, Lebanon.
Pediatr Dermatol. 2010 Sep-Oct;27(5):551-3. doi: 10.1111/j.1525-1470.2010.01276.x. Epub 2010 Aug 26.
Congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) syndrome is a rare X-linked dominant disorder that is characterized by peculiar cutaneous features commonly associated with skeletal and internal organ involvement. Cutaneous verruciform xanthoma is an uncommon cutaneous manifestation of congenital hemidysplasia with ichthyosiform erythroderma and limb defects syndrome. We present a case presenting with a late onset of a large verruciform xanthoma of the right foot, in addition to the more typical cutaneous features of congenital hemidysplasia with ichthyosiform erythroderma and limb defects syndrome.
先天性半侧发育不良伴鱼鳞病样红皮病和肢体缺损(CHILD)综合征是一种罕见的X连锁显性疾病,其特征为独特的皮肤表现,常伴有骨骼和内脏受累。皮肤疣状黄瘤是先天性半侧发育不良伴鱼鳞病样红皮病和肢体缺损综合征一种不常见的皮肤表现。我们报告一例除了具有先天性半侧发育不良伴鱼鳞病样红皮病和肢体缺损综合征更典型的皮肤特征外,还出现右足迟发性巨大疣状黄瘤的病例。