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[Protective effect of hyperbaric hypoxygenation for paraquat poisoning in the rat].

作者信息

Manieri R, Bronzi R, Grilli A, Loffredo B, Data P G, Napolitano L, Felaco M

机构信息

Service d'Anesthésiologie et Réanimation Hôpital S. Camillo, U.L.S. RM10, Rome, Italie.

出版信息

J Toxicol Clin Exp. 1990 Sep-Oct;10(5):297-305.

PMID:2079690
Abstract

The effect to paraquat in normobaric conditions and hyperbaric conditions with either a normal or low (10%) oxygen percentage was investigated in rats. Results showed that hyperbaric conditions increased the toxic effect of paraquat on the lung. By contrast, in hypoxic-hyperbaric conditions, the toxic effect of paraquat was decreased either clinically or macro-/microscopically, and lung injury was reduced.

摘要

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