Kuzin N M, Kashevarov S B, Zavodnov V Ia, Zairov D K, Markov V K
Khirurgiia (Mosk). 1990 Dec(12):46-50.
The authors examined 131 patients with degree III-IV alimentary-constitutional obesity before and after operation for formation of a "small stomach". The average body weight of the patients before surgery was 145 +/- 2.28 kg. In the first 12 postoperative months it reduced by 41.9 +/- 1.76 kg as compared to the initial weight. Diminution of body weight in the second year was statistically insignificant. All patients underwent endoscopy of the esophagus and stomach before and after the operation with appraisal of the degree of macroscopic changes of the mucous membrane. The incidence of chronic gastritis and esophagitis reduced in the postoperative late-term periods more than 1.5 times, that of erosive lesions more than 10 times. Targent measurement of the transmural potential difference (TPD) of the esophagus and stomach was conducted in 36 patients. The TPD value is much less in patients with obesity than in the control group of healthy individuals. After operation the TPD value grows significantly which is due to changes of the diet regimen, reduced amount of the ingested food, reduction of body weight, and improved processes of microcirculation in the mucous membrane of the gastrointestinal tract.
作者对131例III-IV度饮食性体质肥胖患者在接受“小胃”形成手术前后进行了检查。患者术前平均体重为145±2.28千克。术后第一个12个月内，体重较初始体重减轻了41.9±1.76千克。第二年体重减轻在统计学上无显著意义。所有患者在手术前后均接受了食管和胃的内镜检查，并评估了黏膜宏观变化程度。术后晚期慢性胃炎和食管炎的发病率降低了1.5倍以上，糜烂性病变的发病率降低了10倍以上。对36例患者进行了食管和胃跨壁电位差（TPD）的靶向测量。肥胖患者的TPD值远低于健康个体对照组。手术后TPD值显著升高，这是由于饮食方案的改变、摄入食物量减少、体重减轻以及胃肠道黏膜微循环改善所致。
