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血管加压素与人体次最大强度和最大强度运动时的血浆容量反应

Vasopressin and plasma volume response to submaximal and maximal exercise in man.

作者信息

el-Sayed M S, Davies B, Morgan D B

机构信息

Department of Biological Sciences, University of Salford, UK.

出版信息

J Sports Med Phys Fitness. 1990 Dec;30(4):420-5.

PMID:2079849
Abstract

Plasma arginine vasopressin (PAVP), plasma volume loss (PVL) and blood lactic acid (LA) responses to submaximal exercise were examined in 16 normal, healthy individuals. Subjects volunteered to participate in three experiments conducted at the same time of day (9 am) with 7 days intervening between tests. Venous blood was removed before and immediately after 15 min exercise at 40% and 70% VO2max, and before and after 100% VO2max which lasted for 14.3 +/- 1.4 mins (mean +/- SD). The resting mean values of PAVP were similar on the three testing occasions (p greater than 0.05). PAVP rose significantly (p less than 0.05) to all exercise treatments and exhibited an exercise-intensity related response. Similarly, PVL (calculated from changes in haematocrit) and LA responses to exercise were increased with increasing workload. No direct relationship was found between PAVP changes and PVL or LA responses to submaximal exercise (p greater than 0.05). These results suggest that (a) PAVP levels increase to exercise with a response related to exercise intensity; (b) the stimuli generated directly or indirectly to exercise may be one of many factors causing an increase in PAVP.

摘要

对16名正常健康个体进行了研究,检测其在次最大运动量运动时血浆精氨酸加压素(PAVP)、血浆容量损失(PVL)和血乳酸(LA)的反应。受试者自愿参加在一天中同一时间(上午9点)进行的三项实验,每次测试间隔7天。在40%和70%最大摄氧量(VO2max)下运动15分钟前后以及在持续14.3±1.4分钟(平均值±标准差)的100%VO2max运动前后采集静脉血。在三次测试中,PAVP的静息平均值相似(p>0.05)。所有运动处理后PAVP均显著升高(p<0.05),且呈现与运动强度相关的反应。同样,PVL(根据血细胞比容变化计算)和LA对运动的反应也随着工作量增加而增强。在次最大运动量运动时,未发现PAVP变化与PVL或LA反应之间存在直接关系(p>0.05)。这些结果表明:(a)PAVP水平随运动而升高,且与运动强度相关;(b)运动直接或间接产生的刺激可能是导致PAVP升高的众多因素之一。

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