Brau-Javier Cristina N, Sánchez Jorge L
University of Puerto Rico, School of Medicine, Department of Dermatology, PO Box 365067, San Juan, PR 00936-5067.
P R Health Sci J. 2010 Sep;29(3):330-1.
We report the case of a six year-old boy with a history of adrenal cortical carcinoma presenting with cutaneous metastasis. Due to the low incidence of cutaneous metastasis arising from adrenal cortical carcinoma, its diagnosis can be challenging based solely on histological analysis. Yet, the clinical history in combination with an immunohistochemical panel consisting of melan-A, alpha inhibin, D11, caretinin, neuron specific enolase, synatophysin, and chromogranin, can be useful in differentiating it from other tumors with similar cytomorphology.
我们报告了一例患有肾上腺皮质癌病史的6岁男孩出现皮肤转移的病例。由于肾上腺皮质癌引起的皮肤转移发生率较低，仅基于组织学分析进行诊断可能具有挑战性。然而，结合临床病史以及由黑色素A、α抑制素、D11、钙视网膜蛋白、神经元特异性烯醇化酶、突触素和嗜铬粒蛋白组成的免疫组织化学检测组合，有助于将其与具有相似细胞形态学的其他肿瘤区分开来。
