University of Otago, PO Box 7343, Wellington 6242, New Zealand.
Resuscitation. 2010 Dec;81(12):1648-51. doi: 10.1016/j.resuscitation.2010.07.009. Epub 2010 Aug 25.
The effect of cardiopulmonary resuscitation guideline changes on out-of-hospital survival rates and defibrillation efficacy was investigated. The guideline changes were those recommended by the International Liaison Committee on Resuscitation in 2005.
A retrospective comparative study was undertaken of out-of-hospital cardiac arrests in the Wellington region. The effect of guideline changes between the periods of 1st July 2005-30th June 2006 and 1st June 2007-31st May 2008 was examined. Data was collected from Wellington Free Ambulance and hospital records in accordance with the Utstein template. The primary outcome measure was survival to hospital discharge. Additional end points included individual shock success, return of spontaneous circulation (ROSC) and survival to hospital admission.
There was no significant increase in survival to hospital discharge with 11% (18/162) pre-change and 12% (20/170) post-change (p=0.5). First-shock efficacy decreased from 68% (65/96) to 62% (57/92) (p=0.75). Second shock efficacy decreased from 47% (14/30) to 27% (9/33) (p=0.12). The proportion of patients with ROSC increased from 34% (55/162) to 42% (72/170) (p=0.07, Chi squared). The proportion surviving to hospital increased significantly from 22% (36/162) to 36% (61/170) (p=0.006). Withdrawal of atropine in 2005 had no adverse effect on the outcome.
This study suggests that in the Wellington Region of New Zealand, the new guidelines have improved survival to hospital but not to discharge. Whilst the guideline changes have resulted in a trend towards decreased shock success rates, ROSC and survival to hospital admission have both increased.
研究心肺复苏指南变化对院外生存率和除颤效果的影响。指南变化是指 2005 年国际复苏联合会推荐的变化。
对惠灵顿地区院外心脏骤停进行回顾性对比研究。检查 2005 年 7 月 1 日至 2006 年 6 月 30 日和 2007 年 6 月 1 日至 2008 年 5 月 31 日期间指南变化的影响。根据乌斯泰因模板从惠灵顿免费救护车和医院记录中收集数据。主要观察指标是存活至出院。其他终点包括个体电击成功、自主循环恢复(ROSC)和存活至入院。
存活至出院的比例没有显著增加,分别为 11%(18/162)和 12%(20/170)(p=0.5)。首次电击成功率从 68%(65/96)降至 62%(57/92)(p=0.75)。第二次电击成功率从 47%(14/30)降至 27%(9/33)(p=0.12)。ROSC 的患者比例从 34%(55/162)增加到 42%(72/170)(p=0.07,卡方)。存活至入院的比例从 22%(36/162)显著增加到 36%(61/170)(p=0.006)。2005 年停用阿托品对结果没有不利影响。
本研究表明,在新西兰惠灵顿地区,新指南提高了存活率,但未提高出院率。尽管指南变化导致电击成功率、ROSC 和存活至入院率呈下降趋势,但均有所增加。