[化脓性脑膜炎患者血液中的脂质过氧化作用]
[Lipid peroxidation in the blood of patients with suppurative meningitis].
作者信息
Roslyĭ I M, Romm A R, Azizova O A, Vladimirov Iu A
出版信息
Patol Fiziol Eksp Ter. 1990 Jul-Aug(4):40-1.
It is shown that the dynamics of lipid peroxidation (LPO) in patients with purulent meningitis is unspecified in character and is encountered both in meningococcal and pneumococcal infection. The level of secondary LPO products and the degree of hyperfermentemia, which are determined according to the dynamics of changes in the activity of aspartate transaminase, are objective characteristics of the severity of the patient's condition and reach maximum on the 5th day of the disease. The correlation between the dynamics of the primary LPO products and the ceruloplasmin/transferin coefficient allows the severity of the disease to be prognosticated.
结果表明，化脓性脑膜炎患者脂质过氧化（LPO）的动态变化特征不明确，在脑膜炎球菌和肺炎球菌感染中均有出现。根据天冬氨酸转氨酶活性变化动态测定的继发性LPO产物水平和高酶血症程度是患者病情严重程度的客观特征，在疾病第5天达到最高。原发性LPO产物动态与铜蓝蛋白/转铁蛋白系数之间的相关性有助于对疾病严重程度进行预后评估。
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