Bader G, Kulhanek Y, Ziegler-Böhme H
Sektion Chemie, Humboldt-Universität zu Berlin.
Pharmazie. 1990 Jul;45(8):618-20.
Triterpenoid glycosides obtained from Solidago virgaurea L. and Bellis perennis L. (Asteraceae) inhibit the growth of human-pathogenic yeasts (Candida and Cryptococcus species). First results are given of the investigations on the mode of action and the relationships between structure and activity of these compounds. The intensity of growth inhibition is influenced particularly by the carbohydrate chains of the glycosides. Monodesmosidic as well as bisdesmosidic glycosides of polygalacic acid exert fungicidic effects.
从兴安一枝黄花（Solidago virgaurea L.）和雏菊（Bellis perennis L.，菊科）中获得的三萜类糖苷可抑制人类致病性酵母（念珠菌和隐球菌属）的生长。给出了关于这些化合物作用方式以及结构与活性之间关系的初步研究结果。生长抑制强度尤其受糖苷碳水化合物链的影响。聚半乳糖醛酸的单糖苷和双糖苷均具有杀真菌作用。
