Department of Pharmacognosy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Pharmaceutical Technology and Biopharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Molecules. 2019 Jul 23;24(14):2666. doi: 10.3390/molecules24142666.
species are often used in traditional medicine as anti-inflammatory, diuretic, wound-healing and antimicrobial agents. Still, the bioactive compounds and biological activities of some species have not been studied. The present work aimed to investigate the polyphenolic profile and the biological properties of L. Salisb., a poorly explored medicinal plant. The hydroalcoholic extracts from aerial parts were evaluated for total phenolic content (TPC), total flavonoid content (TFC) and the polyphenolic compounds were investigated by HPLC-MS. The antioxidant potential in vitro was determined using DPPH and FRAP assays. Antibacterial and antifungal effects were evaluated by dilution assays and MIC, MBC and MFC were calculated. The results showed that aerial parts contain an important amount of total phenolics (192.69 mg GAE/g) and flavonoids (151.41 mg RE/g), with chlorogenic acid and quercitrin as major constituents. The hydroalcoholic extracts showed promising antioxidant and antimicrobial potential, with potent antibacterial activity against and important antifungal effect against and . The obtained results indicated that the aerial parts of could be used as novel resource of phytochemicals in herbal preparations with antioxidant and antimicrobial activities.
该植物的地上部分含有丰富的总酚（192.69 毫克 GAE/g）和类黄酮（151.41 毫克 RE/g），其中绿原酸和槲皮苷为主要成分。水醇提取物具有良好的抗氧化和抗菌潜力，对具有很强的抗菌活性，对和也有重要的抗真菌作用。研究结果表明，该植物的地上部分可作为具有抗氧化和抗菌活性的草药制剂中植物化学物质的新资源。
