循环嗜铬粒蛋白A作为临床化学中的一种诊断工具。
Circulating chromogranin A as a diagnostic tool in clinical chemistry.
作者信息
O'Connor D T, Takiyyuddin M A, Cervenka J H, Parmer R J, Barbosa J A, Chang Y M, Hsiao R J
机构信息
Department of Medicine, University of California, San Diego.
出版信息
Acta Histochem Suppl. 1990;38:27-33.
PMID:2080246
Abstract
Chromogranin A, measured in the circulation by radioimmunoassay, has emerged as a useful tool in the evaluation of exocytotic sympathoadrenal activity in man, as well as the diagnosis of the presence and extent of neuroendocrine neoplasia. Here we present current thoughts on the structure and function of chromogranin A, and describe known parameters affecting its plasma concentration.
摘要
通过放射免疫测定法在循环系统中测量的嗜铬粒蛋白A，已成为评估人体胞吐性交感肾上腺活动以及诊断神经内分泌肿瘤的存在和范围的有用工具。在此，我们阐述了关于嗜铬粒蛋白A结构和功能的当前观点，并描述了影响其血浆浓度的已知参数。
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