Peschke T, Nagy I, Szállási Z, Schröer H P
GDR Academy of Sciences, Central Institute for Microbiology and Experimental Therapy, Jena.
Acta Histochem Suppl. 1990;39:215-7.
Using K562 tumour cells as model, the effect of cisplatin on cellular morphology and electrolyte balance was examined by scanning electron microscopy and energy-dispersive X-ray microanalysis. The data imply that the membrane surface alterations are a secondary effect following cross-linking reaction of this drug with DNA.
以K562肿瘤细胞为模型，通过扫描电子显微镜和能量色散X射线微分析研究了顺铂对细胞形态和电解质平衡的影响。数据表明，膜表面改变是该药物与DNA交联反应后的继发效应。
