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[儿童干眼症与神经营养性角膜炎。病因与治疗]

[Dry eye syndrome and neurotrophic keratitis in childhood. Causes and therapy].

作者信息

Dietrich T, Renner A B, Helbig H, Oberacher-Velten I M

机构信息

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

出版信息

Ophthalmologe. 2010 Oct;107(10):911-7. doi: 10.1007/s00347-010-2238-0.

Abstract

PURPOSE

The purpose of this review is to enhance the physician's awareness of dry eye syndrome and neurotrophic keratitis in children, to describe the most frequently associated conditions and to discuss the diagnostic and therapeutic options available.

METHODS

A literature review of the pathogenesis of dry eye syndrome and neurotrophic keratitis in children was carried out, clinical cases from our pediatric ophthalmology office are presented as well as therapeutic strategies.

RESULTS

Diseases of the cornea and ocular surface such as dry eye syndrome, neurotrophic keratitis and corneal ulcers are infrequent in children compared to adults. However, they do occur and should be diagnosed and treated as soon as possible in order to prevent long-term complications and amblyopia.

CONCLUSIONS

Inflammatory diseases of the ocular surface can be easily overlooked in children due to the often unknown spectrum of differential diagnoses and the frequently reduced cooperation during examination of young children. Correct and early diagnosis is essential for prevention of long-term complications, e.g. corneal ulceration and scarring.

摘要

目的

本综述的目的是提高医生对儿童干眼症和神经营养性角膜炎的认识,描述最常见的相关病症,并讨论现有的诊断和治疗选择。

方法

对儿童干眼症和神经营养性角膜炎的发病机制进行了文献综述,展示了我们儿科眼科门诊的临床病例以及治疗策略。

结果

与成人相比,儿童中角膜和眼表疾病如干眼症、神经营养性角膜炎和角膜溃疡并不常见。然而,它们确实会发生,应尽快诊断和治疗,以预防长期并发症和弱视。

结论

由于鉴别诊断范围往往不明,且幼儿检查时配合度常常较低,眼表炎症性疾病在儿童中很容易被忽视。正确和早期诊断对于预防长期并发症(如角膜溃疡和瘢痕形成)至关重要。

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