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急性脑脊神经根炎伴1型人类免疫缺陷病毒血清转化

Acute meningoradiculitis concomitant with seroconversion to human immunodeficiency virus type 1.

作者信息

Paton P, Poly H, Gonnaud P M, Tardy J C, Fontana J, Kindbeiter K, Tête R, Madjar J J

机构信息

Hôpital de l'Hôtel-Dieu, Service de Médecine Interne, Lyon, France.

出版信息

Res Virol. 1990 Jul-Aug;141(4):427-33. doi: 10.1016/0923-2516(90)90043-i.

DOI:10.1016/0923-2516(90)90043-i
PMID:2080315
Abstract

We report a case of acute regressive meningoradiculitis concomitant with HIV1 primoinfection. The clinical symptoms were mild and disappeared spontaneously. Electromyographic studies confirmed the regressive demyelinating-type process. The biological diagnosis of HIV1 infection was demonstrated by viral antigen detection, by the presence of the integrated proviral DNA after gene amplification by a polymerase chain reaction, and in particular, by the steady progression in the appearance of different HIV1-specific antibodies. This was shown using three different Western blot kits whose performances were compared.

摘要

我们报告一例急性退行性脑脊神经根炎合并人类免疫缺陷病毒1型(HIV-1)初感染病例。临床症状轻微且自行消失。肌电图研究证实为退行性脱髓鞘型病变过程。通过病毒抗原检测、聚合酶链反应基因扩增后整合的前病毒DNA的存在,特别是通过不同HIV-1特异性抗体出现情况的稳步进展,证实了HIV-1感染的生物学诊断。这是使用三种不同的免疫印迹试剂盒显示的,并对其性能进行了比较。

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