Mendez J A, Vazquez B, Ginebra M P, Gil F J, Manero J M, Planell J A, San Roman J
ICTP, Institute of Polymer Science and Technology, CSIC, Madrid - Spain.
J Appl Biomater Biomech. 2003 Jan-Apr;1(1):48-57.
Partially resorbable self-curing cements based on poly(methyl methacrylate)/phosphate glasses were prepared by mixing methyl methacrylate monomer with poly(methyl methacrylate) powder in different proportions (20-60 wt-%) of phosphate glass (BV11) in the system 44.5-P2 O5 , 44.5-CaO, 11-Na2 O (mol-%). The curing of these formulations showed a reduction of 10 degrees C in the maximum temperature and an increase of 10 minutes in the setting time although the content of residual monomer in the cured materials was unaltered. The presence of the inorganic particles did not significantly change the glass transition temperature of the cement. Static mechanical properties were evaluated in compression. The compressive yield strength of PM-MA/BV11 cements were in the range 110-118 MPa, superior to those of the control for dry specimens. When the test was conducted with wet specimens, a decrease in strength was observed due to the dissolution of the glasses in the medium, but the composites prepared with 20 or 40 wt-% BV11 had the compressive yield strengths required by the international standard for acrylic bone cements (ISO 5833). The dynamic mechanical properties of the formulation containing 60 wt-% BV11 and the corresponding control were evaluated through a fatigue crack propagation test. The results showed that both formulations followed a Paris-Erdogan model in the stable crack propagation, with no significant differences in the value of the exponent m of the mentioned law. Finally, the presence of the phosphate glasses in the acrylic composite did not change the wear damage of the pair UHMWPE/Ti6Al4V produced by the PMMA formulations. (Journal of Applied Biomaterials & Biomechanics 2003; 1: 48-57).
基于聚甲基丙烯酸甲酯/磷酸盐玻璃的部分可吸收自固化骨水泥，是通过将甲基丙烯酸甲酯单体与聚甲基丙烯酸甲酯粉末按不同比例（20 - 60 wt-%）的磷酸盐玻璃（BV11）在44.5-P2O5、44.5-CaO、11-Na2O（mol-%）体系中混合制备而成。这些配方的固化过程显示，最高温度降低了10℃，凝固时间增加了10分钟，尽管固化材料中残留单体的含量未变。无机颗粒的存在并未显著改变骨水泥的玻璃化转变温度。通过压缩试验评估静态力学性能。PM-MA/BV11骨水泥的压缩屈服强度在110 - 118 MPa范围内，优于干燥试样的对照材料。当对湿试样进行测试时，由于玻璃在介质中的溶解，强度出现下降，但用20或40 wt-% BV11制备的复合材料具有丙烯酸骨水泥国际标准（ISO 5833）所要求的压缩屈服强度。通过疲劳裂纹扩展试验评估了含有60 wt-% BV11的配方及其相应对照材料的动态力学性能。结果表明，两种配方在稳定裂纹扩展过程中均遵循Paris-Erdogan模型，上述定律的指数m值无显著差异。最后，丙烯酸复合材料中磷酸盐玻璃的存在并未改变由PMMA配方产生的超高分子量聚乙烯/钛6铝4钒配对材料的磨损损伤。（《应用生物材料与生物力学杂志》2003年；1：48 - 57）
