Winnicott Research Unit, School of Psychology, University of Reading, UK.
J Affect Disord. 2011 Mar;129(1-3):348-53. doi: 10.1016/j.jad.2010.08.002.
Previous research has implicated high levels of antenatal anxiety as a predictor of postnatal depression, but there is a paucity of evidence on the relationship between the various forms of anxiety and postnatal depression. A longitudinal study of 246 mothers (56 with antenatal generalised anxiety disorder (GAD), 68 with antenatal generalised social phobia, 28 with both disorders in the antenatal period, and 94 with no antenatal GAD or social phobia) allowed us to explore whether antenatal social phobia and GAD predict high Edinburgh Postnatal Depression Scale (EPDS) scores (probable depression >12) at 10-14 days, 10-12 weeks, 10 months, 14 months, and 24 months postnatally. We found that, after accounting for the presence of other antenatal anxiety disorders, antenatal depression, maternal age at child's birth, socio-economic status and ethnicity in the models, antenatal GAD independently predicted depression at all time points after delivery. A less robust relationship was found for antenatal social phobia, which predicted postnatal depression at only 10 months after birth. One possibility consistent with our findings is that there may be differences in the timing of postnatal depression with different forms of antenatal anxiety disorders.
先前的研究表明,产前焦虑水平较高是产后抑郁的预测因素,但关于各种形式的焦虑与产后抑郁之间的关系,证据有限。一项对 246 名母亲(56 名患有产前广泛性焦虑症(GAD),68 名患有产前广泛性社交恐惧症,28 名在产前同时患有这两种疾病,94 名无产前 GAD 或社交恐惧症)的纵向研究使我们能够探讨产前社交恐惧症和 GAD 是否预测产后 10-14 天、10-12 周、10 个月、14 个月和 24 个月时 Edinburgh Postnatal Depression Scale(EPDS)评分较高(可能抑郁>12)。我们发现,在模型中考虑了其他产前焦虑障碍、产前抑郁、孩子出生时母亲的年龄、社会经济地位和种族后,产前 GAD 独立预测了所有产后时间点的抑郁。对于产前社交恐惧症,我们发现了一个不太稳定的关系,它只预测了产后 10 个月的抑郁。与我们的研究结果一致的一种可能性是,不同形式的产前焦虑障碍可能会导致产后抑郁的时间不同。