Kolm Isabell, Hofbauer Günther, Braun Ralph P
Dermatologische Klinik, Universitätsspital Zürich, Gloriastrasse 31 CH, Zurich.
Ther Umsch. 2010 Sep;67(9):439-46. doi: 10.1024/0040-5930/a000077.
The skin is the most affected organ by cancer. The incidence rates of skin cancer are steadily increasing, both for melanoma and non-melanoma skin cancers (squamous cell carcinoma, basal cell carcinoma). Over 90 % of the death cases from skin cancers attribute to melanoma. Survival from melanoma is strongly related to tumour thickness. Therefore early detection is the most important step to improve prognosis. In the last years a number of new non invasive techniques for the early diagnosis of melanoma have been developed which are superior to the naked eye examination. In this overview article we present some non-invasive diagnostic techniques like total body photography, digital dermoscopy and confocal microscopy which in addition to dermoscopy assist the dermatologist in differentiating nevi from early melanomas.Non-melanoma skin cancer can be prevented by accurate sun protection. Early squamous cell carcinomas and basal cell carcinomas can be treated either invasively or non-invasively with excellent prognosis.
皮肤是受癌症影响最严重的器官。皮肤癌(包括黑色素瘤和非黑色素瘤皮肤癌,即鳞状细胞癌、基底细胞癌)的发病率正在稳步上升。超过90%的皮肤癌死亡病例归因于黑色素瘤。黑色素瘤的生存率与肿瘤厚度密切相关。因此,早期检测是改善预后的最重要步骤。在过去几年中,已经开发出了一些用于黑色素瘤早期诊断的新型非侵入性技术,这些技术优于肉眼检查。在这篇综述文章中,我们介绍了一些非侵入性诊断技术,如全身摄影、数字皮肤镜检查和共聚焦显微镜检查,这些技术除了皮肤镜检查外,还能帮助皮肤科医生区分痣和早期黑色素瘤。准确的防晒可以预防非黑色素瘤皮肤癌。早期鳞状细胞癌和基底细胞癌可以通过侵入性或非侵入性方法进行治疗,预后良好。