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[头颈部恶性淋巴瘤的表现与管理]

[Manifestations and management of malignant lymphoma in head and neck].

作者信息

Li Qingming, Li Xiangping, He Ying

机构信息

Department of Otolaryngology Head and Neck Surgery, the Fourth Hospital, Shenzhen, 518033, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Jun;24(12):551-3.

Abstract

OBJECTIVE

To explore the clinical feature, treatment and prognosis of malignant lymphoma in head and neck.

METHOD

One hundred and sixteen cases with malignant lymphoma in head and neck were retrospectively analyzed. The predilection site was most in head and neck (39.7%), followed by palate and tonsil (23.3%). The clinical symptoms was different based on different location, painless mass in neck was mostly seen. The misdiagnosis rate is 37.1%. The treatment measures mainly included combined modality therapy and chemotherapy.

RESULT

Among 98 cases, of stage I and II, the survival time of 51 cases was more than one year, 24 cases were more than 3 years, 12 cases were more than 5 years. Eleven patients were lost to follow-up. Among 18 cases, of stage III and IV, 3 patients was lost to follow-up, the other 15 cases were dead after half a year.

CONCLUSION

clinical feature of malignant lymphoma in head and neck is nonspecific and complicated, misdiagnosis most easily occurs. Biopsy is the most valuable in the diagnosis of malignant lymphoma. Combined modality therapy is the mainstay of treatment in malignant lymphoma. The clinical stage classification is important for prognosis.

摘要

目的

探讨头颈部恶性淋巴瘤的临床特征、治疗方法及预后。

方法

回顾性分析116例头颈部恶性淋巴瘤患者。好发部位以头颈部最多(39.7%),其次为腭部和扁桃体(23.3%)。临床症状因部位不同而异,以颈部无痛性肿块多见。误诊率为37.1%。治疗措施主要包括综合治疗和化疗。

结果

98例Ⅰ、Ⅱ期患者中,51例生存时间超过1年,24例超过3年,12例超过5年。11例失访。18例Ⅲ、Ⅳ期患者中,3例失访,其余15例半年后死亡。

结论

头颈部恶性淋巴瘤临床特征非特异性且复杂,极易误诊。活检对恶性淋巴瘤的诊断最具价值。综合治疗是恶性淋巴瘤的主要治疗方法。临床分期对预后至关重要。

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