Lehto I, Ruusuvaara P, Setälä K
Department of Ophthalmology, University of Helsinki, Finland.
Acta Ophthalmol (Copenh). 1990 Dec;68(6):703-9. doi: 10.1111/j.1755-3768.1990.tb01699.x.
Corneal endothelial cell density was determined in 64 eyes (32 patients) with pigmentary glaucoma and in 18 eyes (9 persons) with pigment dispersion syndrome without glaucoma. Twenty-eight healthy eyes served as controls. The glaucomas were stabilized with topical treatment or following laser trabeculoplasty or filtration surgery. The mean duration of the glaucoma was 7.6 years (SD 6.1 years) subsequent to diagnosis. Neither in the glaucomatous, nor in the pigment dispersion syndrome eyes, could any statistically significant difference in cell density be noted compared to the control series. Within the glaucoma group pressure level, topical treatment, laser trabeculoplasty and trabeculectomy did not have any statistically significant effect on cell counts. Distinct pleomorphism and polymegatism of the endothelial cells were observed in the study groups. The endothelial cell density decreased linearly with age.
对64只眼（32例患者）的色素性青光眼以及18只眼（9例患者）无青光眼的色素播散综合征患者测定角膜内皮细胞密度。选取28只健康眼作为对照。青光眼患者经局部治疗、激光小梁成形术或滤过性手术后病情稳定。诊断后青光眼的平均病程为7.6年（标准差6.1年）。与对照组相比，无论是青光眼组还是色素播散综合征组，细胞密度均未发现有统计学上的显著差异。在青光眼组中，眼压水平、局部治疗、激光小梁成形术和小梁切除术对细胞计数均无统计学上的显著影响。在研究组中观察到内皮细胞有明显的多形性和大小不均一性。内皮细胞密度随年龄呈线性下降。
