Hashiba Kiyoshi, Siqueira Pablo R, Brasil Horus A, Moribe Daniel, D'Assunção Marco Aurélio
Endoscopic Unit, Hospital Sírio Libanês Experimental Center , São Paulo, Brazil.
J Laparoendosc Adv Surg Tech A. 2010 Sep;20(7):623-5. doi: 10.1089/lap.2010.0249.
The risk of intraabdominal contamination is a critical consideration during most natural orifice translumenal endoscopic surgery (NOTES) procedures.
The objective of this study was to determine a safe and efficient pathway for the endoscope in a transgastric NOTES procedure.
A pilot experimental study in live pigs was performed.
Five White Landrace pigs, weighing approximately 30-35 kg, underwent the placement of a device consisting of an expandable sheath, the distal portion of which was composed of a fully covered self-expanding metal stent, and an introducer made with an outer catheter, a pushing catheter, and an inner, guiding catheter. The sheath was attached to the stent by suturing it in place. The initial gastric opening was made by means of a needle knife papilotome with electrocoagulation, aimed to the anterior gastric wall. Then, it was dilated with an endoscopic 1.8-cm balloon. The set was introduced over a Savary guidewire. After the set placement, the outer tube was slowly retrieved. Finally, the delivery system was removed from the pig, leaving the entire endoscopic port in place.
The expandable gastric port was placed without difficulty in all animals. Endoscope insertion into the expandable gastric port was very easily performed. The endoscope had a wide range of movement inside the peritoneal cavity. The gastric port sealed the gastric wall, avoiding gross contamination of the peritoneal cavity and maintaining the pneumoperitoneum without excessive inflation of the intestine.
Use of a gastric port can minimize contamination of the peritoneal cavity due to the spillage of gastric contents during a transgastric NOTES procedure and can also facilitate performance of the procedure.
在大多数经自然腔道内镜手术(NOTES)操作过程中,腹腔污染风险是一个关键考量因素。
本研究的目的是确定经胃NOTES手术中内镜的安全有效路径。
在活猪身上进行了一项初步实验研究。
对5头体重约30 - 35千克的大白猪进行手术,植入一种装置,该装置由一个可扩张鞘管组成,其远端部分由一个全覆膜自膨式金属支架构成,还有一个由外导管、推送导管和内引导导管制成的导入器。通过缝合将鞘管固定在支架上。最初通过带有电凝功能的针刀乳头切开器在前胃壁制造胃开口,然后用1.8厘米的内镜球囊进行扩张。该装置通过Savary导丝导入。装置放置好后,缓慢撤回外管。最后,从猪身上移除输送系统,将整个内镜端口留在原位。
在所有动物中均可轻松放置可扩张胃端口。将内镜插入可扩张胃端口操作非常容易。内镜在腹腔内有广泛的活动范围。胃端口封闭胃壁,避免腹腔严重污染,并在不过度充盈肠道的情况下维持气腹状态。
使用胃端口可在经胃NOTES手术期间将胃内容物溢出导致的腹腔污染降至最低,并且还可便于手术操作。