Guédès Antoine, Dangoisse Vincent, Gabriel Laurence, Jamart Jacques, Chenu Patrick, Marchandise Baudouin, Schroeder Erwin
University of Louvain, Division of Cardiovascular Medicine, Cliniques Universitaires de Mont-Godinne, Yvoir, Belgium.
J Invasive Cardiol. 2010 Sep;22(9):391-7.
Despite a proven safety profile, the transradial approach (TRA) for coronary procedures is regarded by many as complicated and the second-choice arterial access, with a high conversion rate to transfemoral access (TFA). This study reports causes of failure and the contemporary success rate of TRA when both radial arteries are attempted first before converting to TFA.
This prospective, single-center study included 1,826 consecutive patients referred for cardiac catheterization, which was performed by two trained operators between January 2005 and June 2007. Procedural data were reported in a specific database.
The procedural success rate through TRA (attempting one or both radial arteries) was 98.8%. One hundred and thirty-five radial attempts failed. Inability to puncture or to wire the artery accounted for 52.6% of failures, inability to reach coronary or graft ostia accounted for 20.7% and the remaining failures were related to the inability to reach a contralateral mammary graft. By multivariate analysis, the best predictors for failures were peripheral artery disease (PAD) (odds ratio [OR] 1.8, 95% confidence interval [CI] 1.1-2.8; p = 0.016), bedside clinical assessment of either a "small radial artery" size (OR 2.6, 95% CI 1.4 to 5.0; p = 0.003) or a "difficult access" (OR 2.5, 95% CI 1.3-4.9; p = 0.006). The number of failed attempts regresses annually by about 40% (OR 0.6, 95% CI 0.4-0.8; p < 0.001), thus demonstrating a continuous learning curve. Although rare, hematoma combined with swelling (3.8%) arises more frequently in females (OR 2.4, 95% CI 1.4-3.9; p = 0.001) and elderly patients (OR 1.9, 95% CI 1.0- 3.7; p = 0.040).
The TRA can be safely proposed for all patients, with a low conversion rate to TFA when an attempt on both radial arteries is considered first.
尽管经桡动脉途径(TRA)已被证明具有安全性,但许多人认为其用于冠状动脉手术较为复杂,是动脉穿刺的第二选择,转为经股动脉途径(TFA)的转化率较高。本研究报告了TRA失败的原因以及在转为TFA之前先尝试双侧桡动脉时TRA的当代成功率。
这项前瞻性单中心研究纳入了1826例连续接受心脏导管插入术的患者,由两名经过培训的操作人员在2005年1月至2007年6月期间进行操作。手术数据记录在特定数据库中。
通过TRA(尝试单侧或双侧桡动脉)的手术成功率为98.8%。135次桡动脉穿刺尝试失败。无法穿刺或导丝进入动脉占失败原因的52.6%,无法到达冠状动脉或移植血管开口占20.7%,其余失败与无法到达对侧乳腺移植血管有关。多因素分析显示,失败的最佳预测因素为外周动脉疾病(PAD)(比值比[OR]1.8,95%置信区间[CI]1.1 - 2.8;p = 0.016)、床边临床评估为“桡动脉细小”(OR 2.6,95% CI 1.4至5.0;p = 0.003)或“穿刺困难”(OR 2.5,95% CI 1.3 - 4.9;p = 0.006)。每年失败尝试次数减少约40%(OR 0.6,95% CI 0.4 - 0.8;p < 0.001),表明存在持续学习曲线。虽然血肿合并肿胀情况罕见(3.8%),但在女性(OR 2.4,95% CI 1.4 - 3.9;p = 0.001)和老年患者(OR 1.9,95% CI 1.0 - 3.7;p = 0.040)中更常见。
对于所有患者都可安全地采用TRA,若首先考虑尝试双侧桡动脉,则转为TFA的转化率较低。