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Nabumetone. Evidence for the lack of enterohepatic circulation of the active metabolite 6-MNA in humans.

作者信息

Brett M A, Buscher G, Ellrich E, Greb W H, Kurth H J, Rülander G, Schmerenbeck B, Haddock R E, Thawley A R

机构信息

Clinical Pharmacology Research Institute, Beecham-Wülfing GmbH & Co KG, Neuss, Federal Republic of Germany.

出版信息

Drugs. 1990;40 Suppl 5:67-70. doi: 10.2165/00003495-199000405-00017.

DOI:10.2165/00003495-199000405-00017
PMID:2081498
Abstract
摘要

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引用本文的文献

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Clinical pharmacokinetics of nabumetone. The dawn of selective cyclo-oxygenase-2 inhibition?萘丁美酮的临床药代动力学。选择性环氧化酶-2抑制的开端?
Clin Pharmacokinet. 1997 Dec;33(6):404-16. doi: 10.2165/00003088-199733060-00001.
2
Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases.萘丁美酮。对其在风湿性疾病中的药理学及治疗应用的重新评估。
Drugs. 1993 Jan;45(1):131-56. doi: 10.2165/00003495-199345010-00009.

本文引用的文献

1
Metabolism of nabumetone (BRL 14777) by various species including man.
Xenobiotica. 1984 Apr;14(4):327-37. doi: 10.3109/00498258409151419.
2
Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent.萘丁美酮(BRL 14777,4-[6-甲氧基-2-萘基]-丁-2-酮):一种新型抗炎药。
J Pharm Pharmacol. 1982 Sep;34(9):562-9. doi: 10.1111/j.2042-7158.1982.tb04794.x.