UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
J Am Med Dir Assoc. 2010 Sep;11(7):468-74. doi: 10.1016/j.jamda.2009.10.007. Epub 2010 Apr 8.
Elderly patients are at an increased risk of developing both hypophosphatemia and hyperphosphatemia. Renal insufficiency predisposes elderly patients to elevated serum concentrations of phosphate. On the other hand, poor dietary intake and loss of phosphorus in the urine can lead to deficiency states. It is well documented that hyperphosphatemia is correlated with an increase in morbidity and mortality as a result of vascular calcification. This article reviews the etiology, pathophysiology, symptoms, and treatment of hypophosphatemia and hyperphosphatemia.
老年患者发生低磷血症和高磷血症的风险增加。肾功能不全使老年患者的血清磷酸盐浓度升高。另一方面，磷的不良饮食摄入和尿液丢失可导致缺乏状态。有充分的文献证明，高磷血症与血管钙化导致的发病率和死亡率增加相关。本文综述了低磷血症和高磷血症的病因、病理生理学、症状和治疗。
