Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire.
Vet Rec. 2010 Sep 4;167(10):364-9. doi: 10.1136/vr.c3206.
Data from 107 cases of pasture-associated laminitis were obtained from first opinion practices to study factors associated with severity, survival and return to ridden exercise. There were 43 mares and 64 geldings, with a median age of 11 years. Of the 107 animals, 33 were small ponies, 45 were large ponies/cobs, 17 were small horses and 12 were large horses. Ninety-seven animals were categorised as having laminitis as defined by Cripps and Eustace (1999): 76 had mild (Obel grade 1 or 2) laminitis and 31 had severe (Obel grade 3 or 4) laminitis. Forty-three animals had previously had laminitis, and were significantly less likely (P=0.02) to have severe laminitis than those that had not. Eighty-nine animals were overweight, and there was a trend (P=0.09) towards severe laminitis cases having a higher body mass index. Eight weeks after disease onset, 102 animals were alive. Lower bodyweight, optimal body condition, mild laminitis and category of acute/chronic founder as defined by Cripps and Eustace (1999) were significantly associated with survival. There was a trend (P=0.06) towards treatment with acepromazine being associated with survival. Of the 81 animals that were used for riding, 48 were being ridden again; this was 2.6 times more likely in animals without previous laminitis. The clinical outcome was judged by a panel of three veterinarians as 'good' in 77 of 107 of cases. Clinical outcome was significantly associated (P=0.03) with horse type: the outcome was 'bad' in none of the small horses, compared with 15 of 45 large ponies/cobs, 11 of 33 small ponies and three of 12 large horses.
从第一意见实践中获得了 107 例牧场相关蹄叶炎病例的数据，以研究与严重程度、存活率和恢复骑行运动相关的因素。其中有 43 匹母马和 64 匹骟马，中位数年龄为 11 岁。在 107 只动物中，33 只为小型马驹，45 只为大型矮马/小型马，17 只为小型马，12 只为大型马。97 只动物被归类为 Cripps 和 Eustace（1999 年）定义的蹄叶炎：76 只患有轻度（Obel 1 或 2 级）蹄叶炎，31 只患有重度（Obel 3 或 4 级）蹄叶炎。43 只动物以前曾患有蹄叶炎，它们患有重度蹄叶炎的可能性明显较低（P=0.02）。89 只动物超重，且重度蹄叶炎病例的体重指数呈升高趋势（P=0.09）。疾病发作后 8 周，102 只动物存活。体重较低、理想体况、轻度蹄叶炎和 Cripps 和 Eustace（1999 年）定义的急性/慢性蹄叶炎类别与存活率显著相关。有一个趋势（P=0.06）表明，接受 acepromazine 治疗与存活率相关。在 81 只可用于骑行的动物中，有 48 只再次被骑行；而以前没有患过蹄叶炎的动物再次被骑行的可能性是其 2.6 倍。由三名兽医组成的小组对 107 例病例中的 77 例进行了临床结局判断，结果为“良好”。临床结局与马的类型显著相关（P=0.03）：在小型马中，无一例为“差”，而在 45 只大型矮马/小型马中，有 15 例为“差”，33 只小型马中有 11 例，12 只大型马中有 3 例。
