Wittemer C, Menard A, Dellenbach P
Service de Gynécologie Obstétrique, Centro Médico-Chirurgical et Obstétrical, Schiltigheim, France.
Hum Reprod. 1990 Nov;5(8):955-8. doi: 10.1093/oxfordjournals.humrep.a137227.
Peritoneal fluid probably has an important and complex role in fertility and infertility. In this study, in-vitro fertilization was attempted in peritoneal fluid and the classical B2-Menezo medium. Clinical criteria concerning male and female fertility and biological factors such as fresh semen quality, sperm survival, sperm-zona pellucida binding, cleavage and pregnancy rates were analysed for each infertile couple. The following results have been obtained. The quality of peritoneal fluid appears to fluctuate greatly from one woman to another. Routine use of peritoneal fluid as a culture medium during in-vitro fertilization should not be encouraged. Peritoneal fluid toxicity may explain some cases of 'unexplained' infertility.
腹膜液在生育和不孕中可能起着重要而复杂的作用。在本研究中，尝试在腹膜液和经典的B2-梅内佐培养基中进行体外受精。针对每对不孕夫妇分析了有关男性和女性生育能力的临床标准以及生物因素，如新鲜精液质量、精子存活、精子与透明带结合、卵裂和妊娠率。得到了以下结果。腹膜液的质量在不同女性之间似乎波动很大。不应该鼓励在体外受精期间常规使用腹膜液作为培养基。腹膜液毒性可能解释一些“不明原因”不孕的病例。
