Wooten James M
Department of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
South Med J. 2010 Oct;103(10):1025-8; quiz 1029. doi: 10.1097/SMJ.0b013e3181f0c866.
Pharmacovigilance is the process of identifying, monitoring, and effectively reducing adverse drug reactions. Adverse drug reactions (ADRs) are an important consideration when assessing a patient's health. The proliferation of new pharmaceuticals means that the incidence of ADRs is increasing. The goal for all health care providers must be to minimize the risk of ADRs as much as possible. Steps to achieve this include understanding the pharmacology for all drugs prescribed and proactively assessing and monitoring those patients at greatest risk for developing an ADR. Groups at greatest risk for developing ADRs include the elderly, children, and pregnant patients, as well as others. Pharmacovigilance must effectively be practiced by all health providers in order to avoid ADRs.
药物警戒是识别、监测并有效减少药物不良反应的过程。在评估患者健康状况时，药物不良反应是一个重要的考量因素。新药物的不断涌现意味着药物不良反应的发生率正在上升。所有医疗保健提供者的目标必须是尽可能降低药物不良反应的风险。实现这一目标的步骤包括了解所有处方药的药理学知识，并主动评估和监测那些发生药物不良反应风险最高的患者。发生药物不良反应风险最高的群体包括老年人、儿童、孕妇以及其他人群。所有医疗保健提供者都必须切实有效地开展药物警戒工作，以避免药物不良反应的发生。
