Zhu Haibao, Chen Huadong, Zhong Yingying, Ren Dandan, Qian Yaling, Tang Hongfang, Zhu Yan
Department of Chemistry, Zhejiang University, Hangzhou 310028, PR China.
J Chromatogr Sci. 2010 Aug;48(7):553-8. doi: 10.1093/chromsci/48.7.553.
Ion chromatography has been proposed for the determination of three common inorganic anions (chloride, nitrate, and sulfate) in nine weak acids (tartaric acid, citric acid, formic acid, acetic acid, metacetonic acid, butyric acid, butanedioic acid, hexafluorophosphoric acid, and salicylic acid) using a single pump, two valves, a single eluent, and a single conductivity detector. The present system uses ion exclusion, concentrator, and anion-exchange columns connected in series via 6-port and 10-port valves in a Dionex ICS-2100 ion chromatograph. The valves were switched for the determination of three inorganic anions from weak acids in a single chromatographic run. Sample matrices of weak acids with a series of concentrations can be investigated. Complete separations of the previously mentioned anions are demonstrated within 40 min. Under the optimum conditions, the relative standard deviation values ranged from 1.3 to 3.8%. The detection limits of the three inorganic anions (S/N = 3) were in the range of 0.3-1.7 microg/L. The recoveries were in the range of 75.2-117.6%. With this system, automation for routine analysis, short analysis time, and low cost can be achieved.
有人提出采用离子色谱法，利用单泵、双阀、单一洗脱液和单一电导检测器，测定9种弱酸（酒石酸、柠檬酸、甲酸、乙酸、间乙酰丙酸、丁酸、丁二酸、六氟磷酸和水杨酸）中的3种常见无机阴离子（氯离子、硝酸根离子和硫酸根离子）。本系统采用离子排斥柱、浓缩柱和阴离子交换柱，通过6通阀和10通阀在戴安ICS - 2100离子色谱仪中串联连接。在一次色谱运行中切换阀门来测定弱酸中的3种无机阴离子。可以研究一系列浓度的弱酸样品基质。在40分钟内实现了上述阴离子的完全分离。在最佳条件下，相对标准偏差值在1.3%至3.8%之间。3种无机阴离子的检测限（信噪比=3）在0.3 - 1.7μg/L范围内。回收率在75.2%至117.6%之间。使用该系统可实现常规分析的自动化、短分析时间和低成本。
