Liu R-Z, Gao J-C, Zhang H-G, Wang R-X, Zhang Z-H, Liu X-Y
Centre for Reproductive Medicine, First Hospital, Jilin University, Changchun, China.
J Int Med Res. 2010 May-Jun;38(3):923-8. doi: 10.1177/147323001003800318.
The aim of this study was to investigate the effect of cigarette smoking on seminal plasma zinc levels and sperm parameters, and to examine the role of seminal plasma zinc. Semen samples from 79 non-smokers and 68 smokers were obtained. There was a significant decrease in seminal plasma zinc in smokers and a clear correlation between seminal plasma zinc levels and the extent of smoking. Sperm parameters (concentration, motility and morphology) among smokers were significantly lower in comparison to non-smokers. These parameters were also significantly decreased among smokers with abnormal zinc levels, while there was no significant difference between non-smokers with normal zinc and non-smokers with abnormal zinc levels. As previous studies have shown that seminal plasma zinc is associated with a decrease of anti-oxidant defences, seminal plasma zinc could be a contributor to the effects of cigarette smoking on sperm parameters. In conclusion, cigarette smoking can affect sperm parameters and this study may help towards providing a mechanistic explanation.
本研究旨在探讨吸烟对精液锌水平和精子参数的影响，并研究精液锌的作用。收集了79名非吸烟者和68名吸烟者的精液样本。吸烟者的精液锌水平显著降低，且精液锌水平与吸烟程度之间存在明显相关性。与非吸烟者相比，吸烟者的精子参数（浓度、活力和形态）显著更低。锌水平异常的吸烟者中这些参数也显著降低，而锌水平正常的非吸烟者与锌水平异常的非吸烟者之间无显著差异。如先前研究所示，精液锌与抗氧化防御能力下降有关，精液锌可能是吸烟影响精子参数的一个因素。总之，吸烟会影响精子参数，本研究可能有助于提供一种机制解释。
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