AstraZeneca Global Research and Development, Silk Road Business Park, Charter Way, Macclesfield, SK10 2NA, UK.
Chem Commun (Camb). 2010 Oct 14;46(38):7145-7. doi: 10.1039/c0cc02440f. Epub 2010 Sep 6.
In the RCM reactions of a series of simple α,ω-dienes, the relative order of reactivity has been unambiguously determined showing that cyclohexene forms faster than cyclopentene or cycloheptene. 1,5-Hexadiene inhibits the RCM of 1,7-octadiene; 1,5-hexadiene cannot progress to the RCM product (cyclobutene) but forms an unexpectedly stable cyclic η(2)-complex.
在一系列简单的α,ω-二烯的 RCM 反应中，反应活性的相对顺序已被明确确定，表明环己烯的形成速度快于环戊烯或环庚烯。1,5-己二烯抑制 1,7-辛二烯的 RCM；1,5-己二烯不能进行 RCM 反应生成（环丁烯），而是形成一种出乎意料的稳定的环状 η(2)-配合物。
