Plant Sciences Department, University of Oxford, Oxford, UK.
Development. 2010 Oct;137(19):3153-65. doi: 10.1242/dev.030049.
Knotted1-like homeobox (KNOX) proteins are homeodomain transcription factors that maintain an important pluripotent cell population called the shoot apical meristem, which generates the entire above-ground body of vascular plants. KNOX proteins regulate target genes that control hormone homeostasis in the meristem and interact with another subclass of homeodomain proteins called the BELL family. Studies in novel genetic systems, both at the base of the land plant phylogeny and in flowering plants, have uncovered novel roles for KNOX proteins in sculpting plant form and its diversity. Here, we discuss how KNOX proteins influence plant growth and development in a versatile context-dependent manner.
结蛋白同源盒（KNOX）蛋白是同源域转录因子，它们维持着一个重要的多能细胞群体，称为茎尖分生组织，它产生维管植物的整个地上部分。KNOX 蛋白调节控制分生组织中激素平衡的靶基因，并与另一类同源域蛋白（称为 BELL 家族）相互作用。在陆地植物系统发育的基础上和在开花植物中，对新的遗传系统的研究揭示了 KNOX 蛋白在塑造植物形态及其多样性方面的新作用。在这里，我们讨论了 KNOX 蛋白如何以多样化的、依赖于情境的方式影响植物的生长和发育。
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