Department of Family and Geriatric Medicine, University of Louisville, Louisville, KY, USA.
J Am Board Fam Med. 2010 Sep-Oct;23(5):647-54. doi: 10.3122/jabfm.2010.05.100031.
Cancers that occur during childhood and adolescence (ages 0 to 19 years) are very responsive to treatment, with a current overall cure rate of better than 80%. However, approximately 75% of childhood cancer survivors develop late effects, including problems with growth and development, vital organ function, reproduction, and psychological health, as well as serious complications of secondary neoplasms and recurrence. The primary physician should continue some level of involvement during all phases of patient care and pay special attention to possible late effects during the follow-up phase.
儿童和青少年时期(0 至 19 岁)发生的癌症对治疗反应非常好,目前整体治愈率超过 80%。然而,约 75%的儿童癌症幸存者会出现晚期效应,包括生长和发育、重要器官功能、生殖和心理健康问题,以及继发肿瘤和复发的严重并发症。初级医生应在患者治疗的所有阶段继续保持一定程度的参与,并在随访阶段特别注意可能出现的晚期效应。