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[大鼠中脑导水管周围灰质刺激诱发的背根电位及其传出通路分析]

[Dorsal root potential evoked by stimulation of periaqueductal gray and its efferent pathway analysis in rats].

作者信息

Zhang A L, Cheng Z F

机构信息

Department of Physiology, Xi'an Medical University.

出版信息

Sheng Li Xue Bao. 1990 Jun;42(3):203-9.

PMID:2082465
Abstract

When periaqueductal gray (PAG) was stimulated with concentric electrodes, a steady negative potential called PAG-DRP was recorded from L5 dorsal root. PAG-DRP with properties of spatial and temporal summation propagates decrementally along the dorsal root and is inhibited by picrotoxin. Lesions of NRM had no effect on the PAG-DRP evoked by stimulation of dorsal PAG, but showed obvious reduction up to about 40% on the PAG-DRP evoked by stimulation of ventral PAG. It is suggested that the descending inhibition of PAG includes some presynaptic inhibition and that the ventral PAG-DRP is relayed partly via NRM while the dorsal PAG-DRP is not associated with NRM.

摘要

当用同心电极刺激导水管周围灰质(PAG)时,从腰5背根记录到一种稳定的负电位,称为PAG - DRP。具有空间和时间总和特性的PAG - DRP沿背根递减性传播,并被印防己毒素抑制。中缝大核(NRM)损毁对刺激背侧PAG诱发的PAG - DRP没有影响,但对刺激腹侧PAG诱发的PAG - DRP有明显降低,可达约40%。提示PAG的下行抑制包括一些突触前抑制,腹侧PAG - DRP部分经NRM中继,而背侧PAG - DRP与NRM无关。

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