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[腹腔粘连。发病机制、预防及治疗的若干问题]

[Abdominal cavity adhesions. Some issues of pathogenesis, prophylaxis and treatment].

作者信息

Tishchenko V V

出版信息

Klin Khir. 2010 Jul(7):32-6.

PMID:20825089
Abstract

The abdominal cavity adhesions (ACA) constitute frequent consequence of various abdominal cavity diseases and traumas and frequent cause of the abdominal adhesive disease and its complications. In spite of the known pathogenesis of ACA, the surgeons had failed throughout the decades of years to find out the measures and methods of its prophylaxis. There are several causes of such a situation and the main of them is that ACA in its origin constitutes a philogenetically developed defense biologic reaction of organism. Because of the fact, that an organism constitutes the self-regulated biological system, any external inputs (including the treatment), directed on qualitative or quantitative signs of these reactions, meet systemic counteraction and become annihilated. The forced overcome of such a counteraction may cause the development of severe systemic disorders in organism. The only prophylactic measures against ACA, which were already tested throughout the time, are the tactical and technical methods, promoting the reduction of severity of morphological changes in peritoneum and abdominal organs, thus causing reduction of natural reaction of organism. When the adhesions formation is inevitable it is necessary to apply surgical methods of governing such a process, and omentoparietopexy may constitutes one of such methods.

摘要

腹腔粘连(ACA)是各种腹腔疾病和创伤的常见后果,也是腹腔粘连性疾病及其并发症的常见原因。尽管已知ACA的发病机制,但几十年来外科医生一直未能找到预防它的措施和方法。造成这种情况有几个原因,其中主要原因是ACA本质上是机体进化而来的一种防御性生物反应。由于机体是一个自我调节的生物系统,任何针对这些反应的定性或定量指标的外部输入(包括治疗)都会遇到全身性的抵抗并被消除。强行克服这种抵抗可能会导致机体出现严重的全身性紊乱。一直以来经过检验的唯一针对ACA的预防措施是一些战术和技术方法,这些方法可促进减轻腹膜和腹部器官形态变化的严重程度,从而降低机体的自然反应。当粘连形成不可避免时,有必要采用手术方法来控制这一过程,而网膜腹壁固定术可能就是其中一种方法。

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