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[大鼠肝叶不同区域肝细胞中糖原的动态合成]

[Dynamic glycogen synthesis in the hepatocytes of different areas of the hepatic lobes in rats].

作者信息

Kudriavtseva M V, Sakuta G A, Shteĭn G I, Kudriavtsev B N

出版信息

Tsitologiia. 1990;32(10):1010-8.

PMID:2082509
Abstract

Using image analyser Magiscan, a quantitative analysis of the total glycogen and of its two fractions was made in hepatocytes of portal and central zones of the liver lobule of rats after a 48 hour starvation and 15, 30, 60, 120 minutes after refeeding. Glycogen content was the lowest after a 48 hour starvation and only a few cells of the central zone contained a noticeable glycogen quantity. Glycogen synthesis initiation began 15 minutes after refeeding. Glycogen synthesis is characterized by a higher glycogen content in the portal zone of liver lobule, and further this difference was even more increased. Different changes were observed in the content of glycogen fractions in the process of glycogen resynthesis after starvation of rats.

摘要

使用图像分析仪Magiscan,对饥饿48小时后的大鼠肝小叶门静脉区和中央区肝细胞中的总糖原及其两个组分进行了定量分析,并在重新喂食后15、30、60、120分钟进行了分析。饥饿48小时后糖原含量最低,中央区只有少数细胞含有明显数量的糖原。重新喂食15分钟后开始糖原合成。糖原合成的特点是肝小叶门静脉区的糖原含量较高,而且这种差异进一步增大。在大鼠饥饿后糖原再合成过程中,糖原组分的含量观察到不同变化。

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