Department of Child and Adolescent Psychiatry, Philipps-University Marburg, Schützenstr. 49, 35039 Marburg, Germany.
J Affect Disord. 2011 Mar;129(1-3):191-7. doi: 10.1016/j.jad.2010.08.011. Epub 2010 Sep 9.
Previous studies analyzed the clinical validity of the Child Behavior Checklist (CBCL) for screening primary depressive disorders (major depression and dysthymia). Other psychiatric disorders with depressive symptomatology (e.g. adjustment disorders with depressive reaction) have not been a research focus to date. This study aims to examine the utility of the CBCL scales Anxious/Depressed and Affective Problems in screening both primary depressive disorders and other disorders with depressive symptomatology.
The two samples consisted of 1445 outpatients and 698 inpatients aged 11-18 who were referred for child and adolescent psychiatric services. The predictive power of the CBCL scales was examined using ROC-analysis.
Both CBCL scales showed small to medium predictive power when screening for primary and other depressive disorders in clinically referred outpatients (AUCs=.694-.780). Within the inpatient sample, only primary depressive disorders were detected with small predictive power different from chance level (AUCs=.625-.673). Both CBCL scales did not differ significantly with regards to predicting depressive disorders.
A limitation of this study is the lack of reliability checks for consensus classification process of the ICD-10 diagnoses. However, comparable prior work using structured interviews resulted in similar AUC values, supporting our findings.
In outpatient samples, the CBCL is suitable for screening other depressive disorders in addition to primary depressive disorders. This is not the case for inpatients due to a misclassification number of 40%; thus using CBCL scales screen for depressive disorders in such populations warrants caution.
先前的研究分析了儿童行为检查表(CBCL)在筛查原发性抑郁障碍(重性抑郁和恶劣心境)方面的临床有效性。其他具有抑郁症状的精神障碍(如伴有抑郁反应的适应障碍)目前尚未成为研究重点。本研究旨在检验 CBCL 量表焦虑/抑郁和情绪问题在筛查原发性抑郁障碍和其他具有抑郁症状的障碍方面的效用。
两个样本包括 1445 名 11-18 岁的门诊患者和 698 名住院患者,这些患者因儿童和青少年精神科服务而就诊。使用 ROC 分析检验 CBCL 量表的预测力。
当筛查临床转诊的门诊患者的原发性和其他抑郁障碍时,两个 CBCL 量表均显示出较小到中等的预测力(AUC 值为.694-.780)。在住院患者样本中,只有原发性抑郁障碍的预测力略有不同,高于机会水平(AUC 值为.625-.673)。两个 CBCL 量表在预测抑郁障碍方面没有显著差异。
本研究的一个局限性是缺乏对 ICD-10 诊断共识分类过程的可靠性检查。然而,使用结构化访谈的类似先前工作得出了相似的 AUC 值,支持了我们的发现。
在门诊样本中,CBCL 除了原发性抑郁障碍外,还适合筛查其他抑郁障碍。但对于住院患者而言并非如此,因为存在 40%的错误分类数;因此,在这些人群中使用 CBCL 量表筛查抑郁障碍需要谨慎。