Fujimoto N, Adachi-Usami E, Yah L H
Department of Ophthalmology, School of Medicine, Chiba University, Japan.
Nippon Ganka Gakkai Zasshi. 1990 Dec;94(12):1157-61.
We studied the effects of miosis on mean sensitivity in cases of glaucoma and normal subjects. The visual field in 30 degrees was measured by an automated perimeter Octopus. The subjects consisted of 13 cases (24 eyes) with open angle glaucoma and 10 normal subjects (10 eyes). Glaucomas had a 1.8dB reduction of mean sensitivity with a decrease in pupil size from greater than 3mm to less than 2mm with 3% or 4% pilocarpine, regardless of age and mean sensitivity. Normal subjects showed a depression of 1.6-1.8dB with a decrease in pupil size from more than 3mm to less than 2mm with 3% pilocarpine. There were no significant changes of mean sensitivity in pupil size over 3mm in normal. There was no difference in the reduction of mean sensitivity with miosis between cases of glaucoma and normal subjects. The mean sensitivity measured under conditions of pupil size over 3mm before glaucoma surgery could be quantitatively compared with that of the pupil after operation.
我们研究了瞳孔缩小对青光眼患者和正常受试者平均敏感度的影响。使用自动视野计Octopus测量30度视野。受试者包括13例(24只眼)开角型青光眼患者和10名正常受试者(10只眼)。无论年龄和平均敏感度如何,使用3%或4%毛果芸香碱使瞳孔大小从大于3mm减小至小于2mm时,青光眼患者的平均敏感度降低1.8dB。正常受试者使用3%毛果芸香碱使瞳孔大小从大于3mm减小至小于2mm时,平均敏感度降低1.6 - 1.8dB。正常受试者瞳孔大小超过3mm时,平均敏感度无显著变化。青光眼患者和正常受试者因瞳孔缩小导致的平均敏感度降低无差异。青光眼手术前瞳孔大小超过3mm时测得的平均敏感度可与术后瞳孔的平均敏感度进行定量比较。