Technispan LLC, 1209 Malbay Drive, Lutherville, Maryland 21093, USA.
Anal Chem. 2010 Oct 1;82(19):8052-9. doi: 10.1021/ac100240t.
The fundamental transport theory for ion mobility spectrometry is modified to include effects of space charge. The new theory is then applied to describing the performance of "inverse ion mobility spectrometry" recently reported in Tabrizchi, M.; Jazan, E. Anal. Chem. 2010, 82, 746-750 using a discharge ionization source. The improved separation capabilities arise from space charge repulsion of the greater number of ions that are introduced into the drift tube by the technique. A larger effective diffusion coefficient and additional displacement velocities for the leading and trailing edges of the ion mobility peak account for the results. Performance is compared to conventional linear ion mobility spectrometry, with and without a radioactive source for ionization.
对离子迁移谱的基本传输理论进行了修正，以纳入空间电荷的影响。然后，新理论被应用于描述最近在 Tabrizchi，M.；Jazan，E. 发表的“逆离子迁移谱”的性能。分析化学。2010, 82, 746-750 使用放电电离源。该技术通过将更多的离子引入漂移管，从而提高了分离能力。较大的有效扩散系数和离子迁移峰的前缘和后缘的附加位移速度解释了实验结果。性能与传统的线性离子迁移谱进行了比较，包括有无放射性源电离。
