Department of Medical Oncology, Sunnybrook Odette Cancer Centre, The University of Toronto, 2075 Bayview Ave., Toronto, Ontario, Canada.
Breast. 2011 Feb;20(1):96-8. doi: 10.1016/j.breast.2010.08.006. Epub 2010 Sep 9.
Breast MRI is often used for surveillance of breast cancer (BC) survivors despite the lack of evidence in this population. We surveyed younger BC survivors to evaluate their willingness to participate in a randomized controlled trial (RCT) of annual digital mammography with or without MRI. Median age of the 348 participants was 51 years; 45% had undergone diagnostic MRI. 22% continued to have surveillance MRI. 58% agreed to consider participating in the proposed RCT; 16% remained neutral. An RCT of MRI surveillance for BC survivors <age 60 is still feasible at centres where annual MRI is not yet routinely recommended.
乳腺磁共振成像(MRI)常用于监测乳腺癌(BC)幸存者,但在该人群中缺乏相关证据。我们对年轻的 BC 幸存者进行了调查,以评估他们是否愿意参与一项年度数字乳腺 X 线摄影与 MRI 联合或不联合应用的随机对照试验(RCT)。348 名参与者的中位年龄为 51 岁;45%的人曾接受过诊断性 MRI 检查。22%的人仍在进行监测性 MRI 检查。58%的人同意考虑参与拟议的 RCT;16%的人保持中立。在尚未常规推荐每年进行 MRI 检查的中心,对年龄<60 岁的 BC 幸存者进行 MRI 监测的 RCT 仍然可行。