澳大利亚抗癫痫药物妊娠登记处：10 年的进展。
The Australian Pregnancy Register of Anti-epileptic Drugs: 10 years of progress.
机构信息
Department of Medicine (RMH/WH), The University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville, Victoria 3050, Australia.
出版信息
J Clin Neurosci. 2010 Dec;17(12):1485-8. doi: 10.1016/j.jocn.2010.05.008. Epub 2010 Sep 9.
The need for collecting a nationwide database for antiepileptic drug (AED) use in pregnancy is described as well as the rationale, methods, funding and logistics of the Australian Pregnancy Register of Anti-epileptic Drugs (APR). Various aspects of treatment with AED have been reported, not only in relation to teratogenicity but also in terms of efficacy of AED, their use in mono and polytherapy, dose-effect relationships and foetal outcomes. The overall effect of the APR in terms of scientific education is also discussed.
描述了为抗癫痫药物（AED）在妊娠中的使用收集全国性数据库的必要性，以及澳大利亚抗癫痫药物妊娠登记处（APR）的原理、方法、资金和后勤。已经报告了 AED 治疗的各个方面，不仅与致畸性有关，而且与 AED 的疗效、单药和多药治疗、剂量-效应关系和胎儿结局有关。还讨论了 APR 在科学教育方面的总体效果。
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