Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Memphis, TN 38163, USA.
Parkinsonism Relat Disord. 2011 Jan;17(1):10-5. doi: 10.1016/j.parkreldis.2010.08.003. Epub 2010 Sep 15.
In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement.
近年来，帕金森病患者胃肠道功能障碍的情况越来越详细。胃肠道的各个层面都可能出现功能异常。体重减轻、牙齿恶化、唾液过多、吞咽困难、胃轻瘫、排便频率减少和肛肠功能障碍都可能发生。这种功能障碍的病理生理基础既包括中枢神经系统又包括肠神经系统的参与。
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