Aesthet Surg J. 2010 Jul-Aug;30(4):549-56. doi: 10.1177/1090820X10380859.
Since the 1980s, there has been an increased interest in autogenous fat grafting for breast augmentation. However, concerns over graft survival and interference with breast cancer screening have limited its application. Since its introduction, refinements in harvesting and grafting techniques have improved results. The available literature consists primarily of case reports and series. There are no controlled trials, and outcomes thus far have not been measured in a standardized way. The limited data relating to breast cancer screening did not note a significant interference. Concerns have been raised that the placement of mature adipocytes and adipocyte-derived stem cells into the hormonally-active environment of the breast may potentiate breast cancer, but there are no clinical trials that investigate this possibility and a consensus regarding the basic science is still developing. Large multicenter, controlled, prospective trials are necessary to further investigate the many issues relating to the application of autogenous fat grafting for augmentation of the breast.
自 20 世纪 80 年代以来，人们对自体脂肪移植隆乳术越来越感兴趣。然而，由于对移植物存活率和对乳腺癌筛查的干扰的担忧，其应用受到了限制。自引入以来，采集和移植技术的改进提高了效果。现有文献主要由病例报告和系列研究组成。没有对照试验，迄今为止，结果并没有以标准化的方式进行衡量。与乳腺癌筛查相关的有限数据没有发现明显的干扰。有人担心，成熟脂肪细胞和脂肪细胞衍生的干细胞被置于乳房的激素活跃环境中可能会促进乳腺癌的发生，但目前还没有临床试验来研究这种可能性，关于基础科学的共识仍在发展中。需要进行大型多中心、对照、前瞻性试验，以进一步研究与自体脂肪移植隆乳术相关的许多问题。
