Nikitina R G, Naidenov Iu P, Malygina A I, Petrik V D
Vopr Onkol. 1978;24(5):3-6.
It is concluded that endolymphatic infusion of X-ray contrast substance in the presence of migrating tumor cells in lymphatic routes is inherent in a potential danger of tumor dissemination. Although getting of tumor cells in blood does not always result in metastases, nevertheless, a due account should be taken of the fact that lymphography is frequently performed in poor immunological resistance patients, preliminarily subjected to chemo- and radiotherapy. The decrease of immune resistance of the organism, in which the lymphatic system is of primary importance, is known to contribute per se to generalization of the tumor process. Another important conclusion is that the principal mass of tumor cells is ejected in the immediate period after endolymphatic injection of X-ray contrast substance. Thus, the cannulation of the thoracic duct during this period may prevent or reduce getting of massive amounts of tumor cells into the total blood flow.
得出的结论是,在淋巴管途径中存在迁移的肿瘤细胞时向内淋巴注入X射线造影剂,本身就存在肿瘤播散的潜在危险。尽管肿瘤细胞进入血液并不总是导致转移,但仍应适当考虑这样一个事实,即淋巴管造影术经常在免疫抵抗力差且预先接受过化疗和放疗的患者中进行。众所周知,机体免疫抵抗力的降低(其中淋巴系统至关重要)本身就有助于肿瘤进程的扩散。另一个重要结论是,肿瘤细胞的主要部分是在向内淋巴注射X射线造影剂后的即刻排出的。因此,在此期间对胸导管进行插管可能会防止或减少大量肿瘤细胞进入全身血流。