Monoclonal antibody Cam 5.2 targeted mainly CK8, but not CK18--Comment on: "Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation--report of a unique case. Int J Clin Exp Pathol. 2010 May 5; 3 (5):534-40.".
作者信息
Leei Chang Kuang, Lin Wea-Lung, Han Chih-Ping
出版信息
Int J Clin Exp Pathol. 2010 Aug 20;3(7):742.
Abstract
摘要
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Anti-Cytokeratin CAM 5.2 (Becton Dickinson) is not synonymous with CK8/18 monoclonal antibody. Comment on "Pancreatic-type mixed acinar-endocrine carcinoma with alpha-fetoprotein production arising from the stomach: a report of an extremely rare case. Med Mol Morphol (2009) 42:167-174".
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J Clin Ultrasound. 2010 Sep;38(7):384; author reply 385. doi: 10.1002/jcu.20724.
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Anticytokeratin CAM 5.2 does not correspond to antibodies CK 8/18.
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The murine monoclonal antibody anti-cytokeratin CAM 5.2 is specific for intracellular cytokeratin 8, not cytokeratin 18.
J Thorac Cardiovasc Surg. 2010 Jun;139(6):1674-5; author reply 1675. doi: 10.1016/j.jtcvs.2009.12.053.
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Antibody to cytokeratin (CK8/CK18) is not derived from CAM5.2 clone, and anticytokeratin CAM5.2 (Becton Dickinson) is not synonymous with the antibody (CK8/CK18).
Hum Pathol. 2010 Apr;41(4):616-7; author reply 617. doi: 10.1016/j.humpath.2010.01.001.
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Anticytokeratin CAM5.2 is not synonymous with CK8/18 monoclonal antibody; and anticytokeratin CAM5.2 can be a marker for cytokeratin 8 but not for cytokeratin 18 and 19.
Am J Surg Pathol. 2010 Apr;34(4):595; author reply 595-6, 596. doi: 10.1097/PAS.0b013e3181cfbfd9.
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CAM5.2 (Becton Dickinson Biosciences) is not synonymous with CK8/18 (Leica Microsystems).
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Cytokeratin 8/18 monoclonal antibody was dissimilar to anti-cytokeratin CAM 5.2.--a comment on: "Discovery of two novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear cell sarcoma and their quantitative evaluation, Experimental and Molecular Pathology 90(2): 194-200, April 2011".
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Anti-cytokeratin CAM5.2 is not a monoclonal antibody against cytokeratin 8/18.
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本文引用的文献
1
Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation - report of a unique case.
Int J Clin Exp Pathol. 2010 May 5;3(5):534-40.
2
Monoclonal antibody to cytokeratin for use in routine histopathology.
J Clin Pathol. 1984 Sep;37(9):975-83. doi: 10.1136/jcp.37.9.975.
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