用于常规组织病理学的细胞角蛋白单克隆抗体。

Makin C A, Bobrow L G, Bodmer W F

J Clin Pathol. 1984 Sep;37(9):975-83. doi: 10.1136/jcp.37.9.975.

CAM 5.2 is a murine monoclonal antibody, raised against the colon carcinoma cell line HT29, which recognises lower molecular weight intracellular cytokeratin proteins within secretory epithelia. Extensive indirect immunohistochemical studies have confirmed that this antibody stains formalin fixed (and freshly frozen) normal and malignant human tissue in a consistent manner. Reliable staining of conventionally processed pathological tissues provides more accurate identification and staging of human malignant epithelial diseases.

CAM 5.2是一种鼠单克隆抗体，由针对结肠癌细胞系HT29产生，可识别分泌上皮内分子量较低的细胞内角蛋白。广泛的间接免疫组织化学研究证实，该抗体以一致的方式对福尔马林固定（以及新鲜冷冻）的正常和恶性人体组织进行染色。对常规处理的病理组织进行可靠染色可为人类恶性上皮疾病提供更准确的识别和分期。