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利用氧作为内源性指示剂通过纳米级高度变化实时监测细胞活力。

Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indicator.

机构信息

Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P. R. China.

出版信息

Chem Commun (Camb). 2010 Oct 21;46(39):7388-90. doi: 10.1039/c0cc01700k. Epub 2010 Sep 7.

DOI:10.1039/c0cc01700k
PMID:20830337
Abstract

A method for real-time evaluation of cell viability was developed by using oxygen as an endogenous indicator in scanning electrochemical microscopy to monitor the nanoscale height change of a single cell in a physiological environment with a novel Pt nanodisk electrode and a newly designed step-approaching strategy.

摘要

采用扫描电化学显微镜(SECM)以氧作为内源性指示剂,开发了一种实时评估细胞活力的方法,并用新型 Pt 纳米盘电极和新设计的逐步逼近策略在生理环境下监测单细胞的纳米级高度变化。

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