Mehrabi A, Fonouni H, Golriz M, Schmied B, Tahmasbirad M, Weitz J, Büchler M W, Zeier M, Schmidt J
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Chirurgische Universitätsklinik Heidelberg, Deutschland.
Chirurg. 2010 Sep;81(9):794, 796-800, 802-3. doi: 10.1007/s00104-009-1873-y.
Due to the existing organ shortage the option of a kidney transplantation (KTx) in patients with end-stage renal disease is not always possible despite the offer of this therapy. So far the required number of KTx could not be adequately achieved by organ donations from deceased persons. To solve this problem living donation KTx programs have already become established in many transplantation centers. In published reports it has been shown that with the living donation program better results could be achieved in terms of graft function and patient survival compared to cadaver donation KTx. Therefore, living donation KTx allows an optimal alternative to expand the organ pool. The aim of our study is to present the long-term results of our living donation KTx program regarding graft function and patient survival. Finally, the risks of living donation KTx will be discussed based on the reported experiences of other centers.
由于目前存在器官短缺的情况,尽管提供了这种治疗方法,但终末期肾病患者进行肾移植(KTx)并非总是可行。到目前为止,已故者器官捐赠无法充分满足所需的肾移植数量。为了解决这个问题,许多移植中心已经建立了活体捐赠肾移植项目。在已发表的报告中表明,与尸体捐赠肾移植相比,活体捐赠项目在移植物功能和患者生存率方面能取得更好的结果。因此,活体捐赠肾移植为扩大器官库提供了一个理想的选择。我们研究的目的是展示我们活体捐赠肾移植项目在移植物功能和患者生存率方面的长期结果。最后,将根据其他中心报告的经验讨论活体捐赠肾移植的风险。