Park K, Moon J I, Kim S I, Kim Y S
Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Transplantation. 1999 Jan 27;67(2):336-8. doi: 10.1097/00007890-199901270-00027.
The donor organ shortage has been one of the major barriers to kidney transplantation in Korea, even though there has been a small but steady flow of cadaveric kidney donations for the last decade. To expand the donor pool in kidney transplantation, we have developed the exchange donor program at our institution and in Korea. The donor exchange program was first started for end-stage renal disease patients who had willing but incompatible related donors due to positive lymphocyte cross-match. The kidney transplantations were performed using exchanged kidneys between two families with successful results. Since this success, we have expanded the donor pool by accepting close relatives, spouses, friends of recipients, and willing voluntary donors as candidates for exchange donors with careful donor screening procedures. It helps relieve stress on donor supply. Particularly in those countries where brain death has not been socially or legally accepted, living donors including related, unrelated, and exchange donors should be considered as potential donors for kidney transplantation to relieve the pressure on donor organ shortage.
尽管在过去十年中韩国尸体肾捐献的数量虽少但较为稳定，但供体器官短缺一直是韩国肾移植的主要障碍之一。为了扩大肾移植的供体库，我们在本院以及韩国开展了交换供体项目。交换供体项目最初是为那些因淋巴细胞交叉配型阳性而有意愿但不相容的亲属供体的终末期肾病患者启动的。肾移植是通过在两个家庭之间交换肾脏进行的，结果很成功。自取得这一成功以来，我们通过接受近亲、配偶、受者的朋友以及自愿的志愿供体作为交换供体候选人，并采用严格的供体筛查程序，扩大了供体库。这有助于缓解供体供应的压力。特别是在那些脑死亡尚未在社会或法律上得到认可的国家，包括亲属、非亲属和交换供体在内的活体供体应被视为肾移植的潜在供体，以缓解供体器官短缺的压力。
