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评估老年受伤患者的死亡率结局的最佳随访时间。

The optimum follow-up period for assessing mortality outcomes in injured older adults.

机构信息

Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon 97239, USA.

出版信息

J Am Geriatr Soc. 2010 Oct;58(10):1843-9. doi: 10.1111/j.1532-5415.2010.03065.x. Epub 2010 Sep 9.

Abstract

OBJECTIVES

To compare mortality rates of hospitalized injured aged 67 and older across commonly used follow-up periods (e.g., in-hospital, 30-day, 1-year) and to determine the postinjury time after which mortality rates stabilize.

DESIGN

Retrospective analysis of Medicare claims.

SETTING

Oregon and Washington Medicare patients.

PARTICIPANTS

Patients admitted to 171 Oregon and Washington facilities during 2001/02 with injuries identified according to International Classification of Diseases, Ninth Revision, code and followed for 1 year.

MEASUREMENTS

The primary outcome was in-hospital mortality and mortality at 30, 60, 90, 180, and 365 days. Kaplan-Meier survival curves and daily postadmission mortality rates were also evaluated. The rate of change (slope) of the survival curves and daily mortality rates were analyzed to select the point after which mortality rates were no longer decreasing.

RESULTS

There were 32,135 injured older adults hospitalized over the 2-year period, with a median age of 82 (interquartile range 77-88). Cumulative in-hospital mortality and at 30, 60, 90, 180, and 365 days was 4.1%, 9.7%, 13.6%, 16.1%, 21.3%, and 28.4%, respectively. Mortality rates stabilized by 6 months after injury, with 89% of the change occurring within 60 days. Although serious injuries, medical comorbidities, and preinjury nursing facility residence were all associated with higher mortality, they did not affect the pattern of mortality after injury.

CONCLUSION

In-hospital mortality is much lower than postdischarge mortality in injured older adults, with a substantial portion of persons dying shortly after discharge from the hospital. Mortality appears to stabilize by 6 months after injury, although 60-day postadmission follow-up captures most of the excess daily mortality rate.

摘要

目的

比较在常用的随访期(如住院期间、30 天、1 年)内,67 岁及以上住院受伤患者的死亡率,并确定死亡率稳定下来的受伤后时间。

设计

对医疗保险索赔进行回顾性分析。

地点

俄勒冈州和华盛顿州的医疗保险患者。

参与者

2001/02 年期间,171 家俄勒冈州和华盛顿州的医疗机构收治的受伤患者,根据国际疾病分类,第 9 版代码确定损伤,并随访 1 年。

测量

主要结局是住院期间死亡率和 30、60、90、180 和 365 天死亡率。还评估了 Kaplan-Meier 生存曲线和每日住院后死亡率。分析生存曲线和每日死亡率的变化率(斜率),以选择死亡率不再下降的时间点。

结果

在 2 年期间,有 32135 名受伤的老年人住院治疗,中位年龄为 82 岁(四分位间距为 77-88 岁)。住院期间和 30、60、90、180 和 365 天的累积死亡率分别为 4.1%、9.7%、13.6%、16.1%、21.3%和 28.4%。受伤后 6 个月死亡率稳定,89%的变化发生在 60 天内。尽管严重损伤、合并症和受伤前疗养院居住均与更高的死亡率相关,但它们并不影响受伤后的死亡率模式。

结论

在受伤的老年人中,住院期间的死亡率远低于出院后的死亡率,其中很大一部分人在出院后不久就死亡。尽管 60 天的住院后随访期可以捕获大部分额外的每日死亡率,但死亡率似乎在受伤后 6 个月稳定下来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8368/2952068/53f76c0bd229/nihms234381f1.jpg

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