Flook E, Izzat S, Ismail A
ENT Department, Hope Hospital, Salford, UK.
J Laryngol Otol. 2011 Jan;125(1):10-2. doi: 10.1017/S0022215110001805. Epub 2010 Sep 10.
Imaging of cholesteatomas can be useful especially in cases of recurrent disease. Computed tomography scans have been recommended before primary surgery, but cholesteatoma tissue looks similar to inflammatory tissue. Diffusion-weighted magnetic resonance imaging is both sensitive and specific in detecting cholesteatoma, which appears as a bright signal on a dark background. Non-echo-planar diffusion-weighted magnetic resonance imaging is superior to routine echo-planar diffusion-weighted magnetic resonance imaging as it minimises susceptibility artefacts; however, the addition of this facility involves expensive magnetic resonance scanner upgrading.
To avoid the cost of such upgrading, we modified our echo-planar diffusion-weighted magnetic resonance imaging parameters and then scanned 15 consecutive cases of suspected cholesteatoma or suspected recurrent cholesteatoma.
Imaging results correlated well with clinical and/or operative findings.
These results indicate that software adjustments can enable echo-planar diffusion-weighted magnetic resonance imaging to detect cholesteatomas reliably, and as effectively as non-echo-planar diffusion-weighted magnetic resonance imaging. This discovery has the potential to facilitate reliable delayed post-operative screening of canal wall up mastoidectomies, avoiding the need for a 'second look' procedure.
胆脂瘤的成像尤其在复发性疾病的病例中可能有用。在初次手术前推荐进行计算机断层扫描,但胆脂瘤组织看起来与炎性组织相似。扩散加权磁共振成像在检测胆脂瘤方面既敏感又特异,胆脂瘤在暗背景上表现为明亮信号。非回波平面扩散加权磁共振成像优于常规回波平面扩散加权磁共振成像,因为它能将磁敏感伪影降至最低;然而,增加此设备需要对磁共振扫描仪进行昂贵的升级。
为避免此类升级的成本,我们修改了回波平面扩散加权磁共振成像参数,然后对15例连续的疑似胆脂瘤或疑似复发性胆脂瘤病例进行扫描。
成像结果与临床和/或手术结果相关性良好。
这些结果表明,软件调整可使回波平面扩散加权磁共振成像可靠地检测胆脂瘤,其效果与非回波平面扩散加权磁共振成像一样有效。这一发现有可能促进对开放式乳突根治术进行可靠的术后延迟筛查,避免“二次探查”手术的需要。